2-(4-bromo-2-(trifluoromethoxy)phenyl)-2,2-difluoroacetic acid - Names and Identifiers
2-(4-bromo-2-(trifluoromethoxy)phenyl)-2,2-difluoroacetic acid - Introduction
2-(4-bromo-2-(trifluoromethoxy)phenyl)-2,2-difluoroacetic acid is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White crystal or crystalline powder
-Molecular formula: C10H6BrF5O3
-Molecular weight: 375.05g/mol
-Melting point: 68-69 ° C
-Boiling point: 315 ° C
-Solubility: Soluble in organic solvents, such as ethanol and dimethyl sulfoxide.
Use:
2-(4-bromo-2-(trifluoromethoxy)phenyl)-2,2-difluoroacetic acid can be used as an intermediate in organic synthesis. It can be used in the synthesis of drugs, pesticides, dyes and other organic compounds. Due to its special structure, it can also be applied in the field of material science.
Method:
A common preparation method is by combining 4-bromo-2-(trifluoromethoxy)phenylboronic acid (4-bromo-2-(trifluoromethoxy)phenylboronic acid) with 2,2-two fluoroacetic acid reaction system. Specific steps include:
1.4-bromo -2-(trifluoromethoxy) benzene boronic acid reacts with potassium carbonate to generate the corresponding potassium salt.
2. The potassium salt reacts with 2,2-difluoroacetic acid to finally generate 2-(4-bromo-2-(trifluoromethoxy)phenyl)-2,2-difluoroacetic acid.
Safety Information:
2-(4-bromo-2-(trifluoromethoxy)phenyl)-2,2-difluoroacetic acid should pay attention to the following safety precautions during use:
-It may be an irritating substance, and the affected area should be rinsed with water immediately after contact.
-Avoid inhaling dust or contact with skin and eyes.
-Wear appropriate protective equipment such as gloves, goggles and protective clothing during use.
-Should be stored in a dark, dry and well-ventilated place, away from combustibles and oxidants.
Last Update：2024-04-09 21:04:16